高压氧对百草枯中毒大鼠的保护作用。

Journal de toxicologie clinique et experimentale Pub Date : 1990-09-01

R Manieri, R Bronzi, A Grilli, B Loffredo, P G Data, L Napolitano, M Felaco

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引用次数: 0

摘要

研究了大鼠在正常或低氧(10%)的常压和高压条件下对百草枯的影响。结果表明，高压环境增加了百草枯对肺的毒性作用。相比之下，在低氧高压条件下，百草枯的毒性作用在临床或宏观/微观上都有所降低，肺损伤减轻。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Protective effect of hyperbaric hypoxygenation for paraquat poisoning in the rat].

The effect to paraquat in normobaric conditions and hyperbaric conditions with either a normal or low (10%) oxygen percentage was investigated in rats. Results showed that hyperbaric conditions increased the toxic effect of paraquat on the lung. By contrast, in hypoxic-hyperbaric conditions, the toxic effect of paraquat was decreased either clinically or macro-/microscopically, and lung injury was reduced.

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Journal de toxicologie clinique et experimentale

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