Antioxidants and antibacterial activity of Glycyrrhiza glabra extract

This study aimed to examine the antioxidants and antibacterial activity of Glycyrrhiza root, stem and leaf extract. The antioxidant activity was determined by measuring total phenolic content (TPC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH). The antibacterial activity was determined using the paper disc method against two bacteria, namely Staphylococcus aureus and Escherichia coli. Results showed part of the plant effect of the antioxidants and antibacterial activity. The results showed that the root sample had significantly (P <0.05) higher total phenol content and antioxidant activity than leaves and stem samples. The TPC value of leaves extract 211.64mg GAE/g dry extract and DPPH 86.36 % was estimated. The antibacterial activity of MeOH extract against the Staphylococcus aureus zone of inhibition was 21.37 mm for root extracts and 8.30 mm against E. coli. The result showed that Glycyrrhiza root, stem and leaf extract were effective against both the bacteria tested with high concentrations. The Glycyrrhiza root, stem and leaf extract can be used to control infectious diseases and prevent oxidative damage. Keywords: Glycyrrhiza glabra, DPPH, TPC, Antibacterial activity