肽功能化长周期光栅光纤微流控系统抗体检测传感器

2022 13th International Symposium on Communication Systems, Networks and Digital Signal Processing (CSNDSP) Pub Date : 2022-07-20 DOI:10.1109/CSNDSP54353.2022.9907987

Chenyang He, Alexander Tarr, Paddy Tighe, S. Korposh, S. Morgan

{"title":"肽功能化长周期光栅光纤微流控系统抗体检测传感器","authors":"Chenyang He, Alexander Tarr, Paddy Tighe, S. Korposh, S. Morgan","doi":"10.1109/CSNDSP54353.2022.9907987","DOIUrl":null,"url":null,"abstract":"A long period grating (LPG) optical fibre sensor modified coated with an Immunoglobulin G (IgG)-binding peptide is reported. The IgG-binding peptide provides a controllable binding affinity towards IgG which is comparable to antibody-antigen interaction due to the non-covalent bonds of the peptide’s amino acid enabling development of a reversible optical fibre immunosensor. A microfluidic system has been developed for reliable flow of liquid over the sensor.","PeriodicalId":288069,"journal":{"name":"2022 13th International Symposium on Communication Systems, Networks and Digital Signal Processing (CSNDSP)","volume":"9 4","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Peptide Functionalized Long Period Grating Optical Fibre Sensor for Antibody Measurement with Microfluidic System\",\"authors\":\"Chenyang He, Alexander Tarr, Paddy Tighe, S. Korposh, S. Morgan\",\"doi\":\"10.1109/CSNDSP54353.2022.9907987\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A long period grating (LPG) optical fibre sensor modified coated with an Immunoglobulin G (IgG)-binding peptide is reported. The IgG-binding peptide provides a controllable binding affinity towards IgG which is comparable to antibody-antigen interaction due to the non-covalent bonds of the peptide’s amino acid enabling development of a reversible optical fibre immunosensor. A microfluidic system has been developed for reliable flow of liquid over the sensor.\",\"PeriodicalId\":288069,\"journal\":{\"name\":\"2022 13th International Symposium on Communication Systems, Networks and Digital Signal Processing (CSNDSP)\",\"volume\":\"9 4\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-07-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2022 13th International Symposium on Communication Systems, Networks and Digital Signal Processing (CSNDSP)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/CSNDSP54353.2022.9907987\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2022 13th International Symposium on Communication Systems, Networks and Digital Signal Processing (CSNDSP)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CSNDSP54353.2022.9907987","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

摘要

报道了一种免疫球蛋白G (IgG)结合肽包被改性的长周期光栅(LPG)光纤传感器。IgG结合肽提供了与IgG的可控制的结合亲和力，这与抗体-抗原相互作用相当，因为肽的氨基酸的非共价键使得开发可逆光纤免疫传感器成为可能。为了保证传感器上液体的可靠流动，研制了一种微流体系统。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Peptide Functionalized Long Period Grating Optical Fibre Sensor for Antibody Measurement with Microfluidic System

A long period grating (LPG) optical fibre sensor modified coated with an Immunoglobulin G (IgG)-binding peptide is reported. The IgG-binding peptide provides a controllable binding affinity towards IgG which is comparable to antibody-antigen interaction due to the non-covalent bonds of the peptide’s amino acid enabling development of a reversible optical fibre immunosensor. A microfluidic system has been developed for reliable flow of liquid over the sensor.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

2022 13th International Symposium on Communication Systems, Networks and Digital Signal Processing (CSNDSP)

自引率

0.00%

发文量