S. Matsumoto, S. Ono, Saori Shinoda, Chika Kakuta, S. Okada, Takashi Ito, T. Numata, T. Endo
{"title":"GET途径介导错误定位的尾锚蛋白从线粒体转移到内质网","authors":"S. Matsumoto, S. Ono, Saori Shinoda, Chika Kakuta, S. Okada, Takashi Ito, T. Numata, T. Endo","doi":"10.1083/jcb.202104076","DOIUrl":null,"url":null,"abstract":"Tail-anchored (TA) membrane proteins mistargeted to mitochondria are extracted by Msp1 and then transferred to the ER for further quality control. Matsumoto, Ono, et al. show that this retransfer of mistargeted TA proteins requires the operation of the GET system.","PeriodicalId":343306,"journal":{"name":"The Journal of Cell Biology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"GET pathway mediates transfer of mislocalized tail-anchored proteins from mitochondria to the ER\",\"authors\":\"S. Matsumoto, S. Ono, Saori Shinoda, Chika Kakuta, S. Okada, Takashi Ito, T. Numata, T. Endo\",\"doi\":\"10.1083/jcb.202104076\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tail-anchored (TA) membrane proteins mistargeted to mitochondria are extracted by Msp1 and then transferred to the ER for further quality control. Matsumoto, Ono, et al. show that this retransfer of mistargeted TA proteins requires the operation of the GET system.\",\"PeriodicalId\":343306,\"journal\":{\"name\":\"The Journal of Cell Biology\",\"volume\":\"25 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-04-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Cell Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1083/jcb.202104076\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Cell Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1083/jcb.202104076","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
GET pathway mediates transfer of mislocalized tail-anchored proteins from mitochondria to the ER
Tail-anchored (TA) membrane proteins mistargeted to mitochondria are extracted by Msp1 and then transferred to the ER for further quality control. Matsumoto, Ono, et al. show that this retransfer of mistargeted TA proteins requires the operation of the GET system.