Víctor Parra-Monreal, María A. Ortega-Machuca, J. Ramón‐Azcón, W. Svendsen, A. Romano-Rodríguez, Mauricio Moreno-Sereno
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Detection of cytokines in skeletal muscle tissue using optical SPR sensing platform
In this work we have explored the use of a Surface Plasmon resonance (SPR) phenomenon for the detection of interleukin-6 (IL-6), a pro-inflammatory cytokine. It plays an important role in the muscle tissues, having direct relation with muscle contraction and, thus, it is considered a biomarker for some types of muscular dystrophies. Here we show that SPR can be used as a real-time monitoring of the shift of the reflectance dip of a gold diffraction grating in front to the antibody adhesion to gold.
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