Evaluation of the Effect of Platelet Rich Plasma on the Rate of Maxillary First Molars Distalization; A Randomized Clinical Trial

Objective to evaluate the effect of platelet rich plasma (PRP) on the rate of maxillary first molars distalization. Materials and methods: twenty class II subjects of age range between 19-30 years who required bilateral maxillary first molars distalization as a part of their orthodontic treatment were randomly allocated into two equal groups: PRP group and control group. Distalization was carried out with a miniscrew implant-aided modified transpalatal bar appliance. The PRP group received PRP injection on the day of distalization appliance placement. Digital models were obtained every four weeks to evaluate the rate of maxillary first molars distal movement for a period of six months. Results: the control group showed a statistically significant higher rate of distal movement of the first molars compared to the PRP group from the third to the sixth month of the study. Conclusion: The PRP did not accelerate the rate of maxillary first molars distalization. It rather decreased the rate of distalization