Kehan Lin, Hengxi Liu, Junying Li, Chenhao Shou, Yi-Feng Xia, M. Chu, Xi Chen
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引用次数: 0
摘要
这项研究的测序读数来自Aaron J. Wilk分享的研究。我们对B淋巴细胞数据进行了深入分析。共列出了2126个差异表达基因。通过GO富集分析，筛选出24个与B淋巴细胞功能相关的簇，主要富集在10条与免疫调节功能相关的KEGG信号通路中，表达差异显著的基因。这提示在Sars-Cov2感染过程中，B淋巴细胞免疫过程中免疫调节基因的表达存在差异。
Differential gene expression in B lymphocyte immune process induced by COVID-19 infection
The Sequencing reads of this study are derived from research shared by Aaron J. Wilk. We conducted a deep analysis of B lymphocyte data. A total of 2126 differentially expressed genes were listed out. Through GO enrichment analysis, 24 clusters related to B lymphocyte functioning were screened out, and genes with significant differential expression were mainly enriched in 10 KEGG signaling pathways related to immune regulatory functions. This suggests that there are differences in the expression of immune regulatory genes in the immune process of B lymphocytes during the Sars-Cov2 infection.
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