白内障晶状体蛋白的翻译后修饰。

Lens and eye toxicity research Pub Date : 1991-01-01

J J Harding

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引用次数: 0

摘要

1990年8月在波兰比得哥什举行的一次会议上报告了支持晶状体蛋白翻译后非酶修饰在白内障中的作用的证据。糖基化和氨甲酰化是近年来研究的热点。这两种方法都能产生具有类似于蛋白质折叠和展开途径的“熔融球”中间体性质的修饰蛋白。

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Post-translational modification of lens proteins in cataract.

Evidence supporting the role of non-enzymic post-translational modification of lens proteins in cataract is reported as presented at a meeting in Bydgoszcz, Poland in August 1990. Glycation and carbamylation have been studied intensively recently. Both produce modified proteins with properties similar to those of 'molten-globule' intermediates of protein folding and unfolding pathways.

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Lens and eye toxicity research

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