牙干细胞在牙科中的应用:进展如何?

K. Mokhtar
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引用次数: 0

摘要

牙干细胞(Dental Stem Cells, DSC)的应用已经得到了其他领域的广泛认可,但它似乎与牙科有着密切的联系。DSC是从牙组织中获得的未分化细胞。具体来说,这些未分化的细胞具有多能分化为特定谱系的能力。这些干细胞是间充质干细胞(MSC),从特定的牙齿组织中获取,例如从恒牙的牙髓中获取;牙髓干细胞(DPSC),乳牙的牙髓;人脱落乳牙干细胞(SHED)和牙周韧带干细胞;PDLSC(牙周韧带干细胞)。从人第三磨牙牙囊中也可获得其他牙干细胞;DFSC(牙滤泡干细胞)和来自根尖乳头;SCAP (Stem Cells from Apical Papilla) (Abdullah et al., 2013;Botelho et al., 2017)。其中,DPSCs和shed是在组织工程和再生研究中得到广泛应用的牙干细胞。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Application of dental stem cell in dentistry: where are we now?
Dental Stem Cells (DSC) appears to be closely linked to dentistry although the application of DSC has been widely acknowledged by other fields. DSC are undifferentiated cells obtained from the dental tissue. Specifically, these are undifferentiated cells with multipotential ability to differentiate into specific lineages. These stem cells are mesenchymal stem cell (MSC) which are harvested from specific dental tissues such as from the dental pulp of permanent teeth; DPSC (Dental Pulp Stem Cells), dental pulp of deciduous teeth; SHED (Stem Cell from Human Exfoliated Deciduous teeth) and from the periodontal ligament; PDLSC (Periodontal Ligament Stem Cells). Other dental stem cells could also be obtained from dental follicle of human third molar; DFSC (Dental Follicle Stem Cells) and from the apical papilla; SCAP (Stem Cells from Apical Papilla) (Abdullah et al., 2013; Botelho et al., 2017). Of these, DPSCs and SHEDs are dental stem cells which have been utilized in many of the tissue engineering and regeneration research.
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