静脉注射免疫球蛋白成功治疗顽固性舞蹈病1例

A. Güven, M. Oflaz, A. Kaya, F. Bolat, Utku Aygüneş, F. D. İçağasıoğlu
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引用次数: 1

摘要

西德纳姆氏舞蹈病(SC)是儿童获得性舞蹈病的常见病因。SC主要发生在未经治疗的链球菌感染儿童中。用于治疗这种疾病的有效治疗方法有:抗癫痫药物(丙戊酸、卡马西平等)、氟哌啶醇、氯丙嗪、安非他明、类固醇、血浆交换和静脉注射免疫球蛋白(IVIG)。我们报告一个12岁的女孩心脏炎和严重的广泛性舞蹈病,并成功地治疗IVIG。本病例报告显示,IVIG是抗惊厥药、多巴胺拮抗剂和类固醇耐药的舞蹈病病例的有效治疗方法,尽管需要更大规模的研究来证实这一结论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Resistant Chorea Successfully Treated with Intravenous Immunoglobulin: A Case Report
Sydenham’s chorea (SC) is common cause of acquired chorea in childhood. SC occurs mainly in children with untreated streptococcal infections. An effective list of therapeutic options has been used to treat this disorder: antiepileptic drugs (valproic acid, carbamazepine etc.), haloperidol, chlorpromazine, amphetamines, steroids, plasma exchange and intravenous immunoglobulins (IVIG). We report a 12-year-old girl with carditis and severely generalized chorea and successfully treated with IVIG. This case report shows that IVIG is an effective treatment for the chorea cases resistant to anticonvulsants, dopamine antagonists and steroids, although larger studies are needed to confirm this conclusion.
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