Durga Darshene Kunasegran, Kohila Gengatharan, Rani Thanuja Logeswaran, Viknesuwary Subramaniam, D. Naik
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引用次数: 2
摘要
已知冠状病毒会导致致命疾病,如严重急性呼吸系统综合症(SARS)、中东呼吸综合征(MERS)和最近发现的冠状病毒19 (COVID-19)。它是由一种单链RNA病毒——严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)引起的传染病。本综述旨在研究COVID-19患者的临床表现和合并症。相关文章在PubMed、Science direct、JAMA特刊、New England Journal of Medicine中检索。只有选定的论文被用于数据提取和综合。当前Covid-19大流行的确切来源尚不清楚。主要临床症状为发热、干咳、肌痛、呼吸困难。其他症状包括头痛、不适、寒战/僵硬和腹泻。60岁以上伴有合并症者死亡率较高。数据分析显示,不同地区的死亡率各不相同。COVID-19的死亡率在患有合并症的老年人中最高。
Coronaviruses are known to cause fatal diseases like Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS) and recently recognised coronavirus disease 19 (COVID-19). It is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a single-stranded RNA virus. This review is done to study the clinical presentation, comorbid conditions in COVID-19 patients. The relevant articles were searched in PubMed, Science direct and special issues in JAMA, and the New England Journal of Medicine. Only selected papers were used for data extraction and synthesis. The exact source of current pandemic of Covid-19 is not known. The main clinical symptoms include fever, dry cough, myalgia, dyspnoea. Other symptoms presented are headache, malaise, chills/rigor and diarrhoea. The mortality rate was high in above 60 years of age with the comorbid conditions. The data analysis revealed varied mortality rates in different regions. The mortality rate of COVID-19 has been highest among elderly individuals with the comorbid conditions.