Evaluation of alveolar ridge preservation using Platelet-Rich Fibrin with Leukocytes

Objective: To evaluate the alveolar ridge preservation using platelets-rich fibrin with leukocytes covered by collagen membrane. Subjects and Methods: Forty patients have one of maxillary premolars indicated for extraction were selected and divided into two groups Study group: consisted of 20 extraction sockets that received L-PRF covered by collagen membrane. Control group: consisted of 20 extraction sockets as a control. Patient will be followed at 3,7 and 14 days to evaluate the healing index. Bone density and dimensional changes will be evaluated by (CBCT) after 3 and 6 months. Results: The vertical bone and horizontal bone resorption showed a statistically significant decrease in study group than control by (study: 6,1 %, control 10 %) at 3 months. The bone density was increased in both groups after 3 and 6 months, however it was a statistically significant increase in study group than control the healing is improved with a statistically significant increase in the second week than the first week in both groups. Conclusion: using of leukocyte with platelet rich fibrin (L-PRF) together with collagen membrane accelerates the formation of bone filling in the extraction bony socket, increasing its density and minimizing its dimensional change.