传统TESE技术:9年单中心经验回顾

D. Hauptman, T. Hudolin, Z. Zimak, T. Kuliš, D. Ježek, Z. Kastelan
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引用次数: 1

摘要

不孕症的定义是性活跃、未采取避孕措施的夫妇在一年内无法实现自然怀孕(世界卫生组织)。据估计,有15-20%的不孕夫妇,而且这一数字还在增加,使不孕症成为一个主要的社会人口全球问题。在过去,女性因素被认为是主要原因,但今天我们知道男性不育约占50%的病例。因此,建议男女同时治疗。男性不育症最严重的情况是无精子症,在一般人群中发生率为1%,而在不育男性人群中发生率为10-20%。无精子症可分为阻塞性(OA)和非阻塞性(NOA)。在无精子症的各种治疗方案中,睾丸活检(TESE)提供了最佳的精子回收机会。TESE可以通过经典(传统的,开放的)方法或使用手术显微镜进行,即显微外科TESE (mTESE)。mTESE是保留给最复杂的患者遗传疾病或以前精子提取失败在传统的TESE程序。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Conventional TESE technique: A short review and a single-centre experience in 9 years
: Infertility is defined as the inability of a sexually active, non-contraceptive couple to achieve spontane-ous pregnancy within one year (Word Health Organisation). It is estimated that there are 15-20% of infertile couples, and this number is increasing, making infertility a major socio-demographic global problem. In the past, female factors were thought to be the main causes, but today we know that male infertility accounts for about 50% of cases. Therefore, simultaneous treatment of both sexes is recommended. The most severe condition of male infertility is azoospermia, which occurs in the general population in 1%, while in infertile male populations it occurs in 10-20% of cases. Azoospermia can be obstructive (OA) and non-obstructive (NOA). Among various treatment options for azoospermia, testicular biopsy (TESE) provides the best chance of sperm retrieval. TESE can be done by classical (conventional, open) approach or using an operating microscope, microsurgical TESE (mTESE). mTESE is reserved for the most complex patients with genetic disorders or previously sperm retrieval failure during conventional TESE procedure.
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