[仔猪产后早期骨髓细胞红系菌落的形成及其对体外促红细胞生成素(EP)的敏感性]。

Polskie archiwum weterynaryjne Pub Date : 1991-01-01
F Przała, T Bakuła, M Gajecki, E Zduńczyk, E Skorska-Wyszyńska
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引用次数: 0

摘要

在仔猪出生后第1小时(0、6、12、24、48)和第3、5天(3、5)采集骨髓,体外培养48、72小时,评估分离骨髓细胞的发育效率和形成红系集落的能力(cfu - e集落形成单元),并检测红细胞对Ep添加的敏感性。结果表明,新生仔猪骨髓中红细胞集落(CFU-E)形成能力强,但对促红细胞生成素(Ep)的敏感性较低。12小时后形成红系未成熟菌落的效率有限,24小时后形成成熟菌落的效率也有限。观察到的变化可能是由于红细胞对Ep的敏感性有限引起的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Formation of erythroid colonies of bone marrow cells and their sensitivity to erythropoietin (EP) (in vitro) in piglets during the early postnatal period].

Collected at the first hours (0, 6, 12, 24, 48) and days (3 and 5) of piglets life bone marrow was cultured (in vitro) during 48 and 72 hours in order to assess the efficiency of development and ability of isolated marrow cells to form erythroid colonies (CFU-E-Colony Forming Unit) and also to examine the erythroidal sensitivity to Ep addition. It was found that bone marrow of new born piglets shows high ability to form erythroid colonies (CFU-E), but low sensitivity to Ep (erythropoietin). The limited efficiency to form immature erythroid colonies following 12h as well as matured ones after 24h, has been also shown. Observed changes could be caused by the limited erythroidal cells sensitivity to Ep.

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