Pethidine Infiltration in Intra Fascial Layer After Abdominal Hysterectomy

Introduction: multimodal analgesia regimen has a cornerstone component involving local wound infiltration with analgesic agents to manage and enhance post-operative pain to increase patient satisfaction. Aim: assessment and evaluation of effectiveness of local pethidine infiltration as a local analgesic in total abdominal hysterectomy. Methodology: A cohort of 151 cases that have undergone abdominal hysterectomy have been categorized randomly into two research groups research group I (n=74 cases), involved women that were administered both wound infiltration and IM pethidine; and research group II (n=77 cases), involving women that were administered IM pethidine. Results: The median 10-cm VAS for postoperative pain was significantly lower in women who received both WI and IM pethidine when compared to women who received only IM pethidine, 1 hour, 6 hours, 12 hours and 24 hours postoperatively. The mean total morphine consumption was lower in women who received both WI and IM pethidine when compared to women who received only IM pethidine. Conclusion: Pethidine when administered in a simultaneous manner intrafascially and intramuscularly in cases undergoing total abdominal hysterectomy is more effective in reducing post-operative pain levels