糖尿病患者红细胞总钙含量、胞质游离钙及红细胞膜动态特性。

G Caimi, A Serra, R Lo Presti, G Grifo, A Romano, A Galluzzo, A Sarno
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引用次数: 0

摘要

在一组细分为1型和2型的糖尿病患者中(12例1型和12例2型),我们评估了红细胞总钙含量、红细胞胞质游离钙、红细胞膜流动性和红细胞膜蛋白横向流动性。从所获得的结果来看,很明显,红细胞总钙含量不能区分正常人与1型和2型糖尿病患者,而红细胞胞质游离钙确实可以区分这些糖尿病类型。红细胞膜流动性和红血球蛋白横向流动性区分正常人和1型和2型糖尿病患者。在正常人和1型和2型糖尿病患者中,红细胞总钙含量、膜流动性和膜蛋白横向迁移之间没有明显的关系。红细胞胞质游离钙值与反映红细胞动态特性的参数之间存在轻微但显著的负相关,仅在2型糖尿病患者中存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Total red cell calcium content, cytosolic red cell free calcium and erythrocyte membrane dynamic properties in diabetes mellitus.

In a group of diabetics subdivided for type (12 of type 1 and 12 of type 2), we evaluated the total red cell Ca content, red cell cytosolic free calcium, erythrocyte membrane fluidity and erythrocyte membrane protein lateral mobility. From the results obtained, it is evident that the total red cell Ca content does not discriminate normals from type 1 and 2 diabetics, whereas the red cell cytosolic free calcium does differentiate between these diabetic types. Erythrocyte membrane fluidity and erythrocyte protein lateral mobility discriminate normals from type 1 and 2 diabetics. In normals and in diabetics of type 1 and 2, no relationship is evident between total red cell Ca content, membrane fluidity and membrane protein lateral mobility. A slight, but significant negative correlation between red cell cytosolic free calcium values and parameters reflecting the red cell dynamic properties is present in type 2 diabetics only.

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