利用现代数字技术评估帕金森病前驱期生物标志物及其在疾病进展中的作用

Proceedings of the 6th International Conference on Future Networks & Distributed Systems Pub Date : 2022-12-15 DOI:10.1145/3584202.3584262

K. M. Daminova, Rustam Zhumanazarovich Matmurodov, D. Akramova, G. Khamdamova, Gulizahro Turayeva, Madina Kamilovna Abdullayeva, Bobur Batirovich Valiyev, Zokir Rustamovich Sodiqov, Anvar Aidjonovich Hudoyorov, N. Tilabov

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引用次数: 0

摘要

本文报告213例PD患者的观察结果，其中女性90例(42.25%)，男性123例(57.75%)，平均年龄46.17±0.63岁。根据英国脑库“帕金森病协会脑库”的国际标准选择PD患者。患者接受了脑部CT或MRI检查。嗅觉干扰由Burchard (Hamburg, Germany)使用Sniffin Stix Test (SST)进行研究。所有患者均行耳鼻喉检查。研究结果表明，早发性PD患者体内存在低血血症是“帕金森”型潜在神经退行性过程的重要生物标志物，因此也是PD未来发展的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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EVALUATION OF PRODROMAL STAGE BIOMARKERS IN PARKINSON'S DISEASE AND THEIR ROLE IN DISEASE PROGRESSION USE OF MODERN DIGITAL TECHNOLOGIES

The article presents the results of observation of 213 patients with PD, including 90 (42.25%) women, 123 (57.75%) men, whose mean age was 46.17±0.63 years. Patients with PD were selected in accordance with the international criteria of the British brain bank "Parkinson's Disease Society Brain Bank". Patients underwent CT or MRI of the brain. Olfactory disturbances were studied using the Sniffin Stix Test (SST) by Burchard (Hamburg, Germany). All patients underwent examination of the ENT organs. The results obtained indicate that the presence of hyposmia in patients with early onset of PD is an important biomarker of the latent neurodegenerative process of the “Parkinsonian” type and, therefore, the risk of future development of PD.

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Proceedings of the 6th International Conference on Future Networks & Distributed Systems

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