{"title":"[标准化控制抗结核治疗和结果755例患者]。","authors":"B Wiesner, G Cramer, U Hamel, G Roth","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>755 patients were treated because of tuberculosis from 1984-1989. The treatment was standardized according to the recommendations. INH and RMP were used in over 95% as in the hospital as in the ambulatory phase. During the period of 6 yrs. the use of SM was markedly reduced (21.8%) while the use of PZA increased from 14.6% to 55.0%. At least four drugs were used in 22.5%. In 36.2% mycobacteria were found only before starting treatment. After four weeks treatment further 45.1% were negative. Adverse reactions were registered in 9.3%. Concomitant diseases rendering the treatment were observed in 24.7%. Ten patients died because of tuberculosis. Until now only 3 patients had relapses. Controlled treatment is valuable and therefore recommended.</p>","PeriodicalId":76840,"journal":{"name":"Zeitschrift fur Erkrankungen der Atmungsorgane","volume":"177 1-2","pages":"71-5"},"PeriodicalIF":0.0000,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Standardized controlled antitubercular therapy and results in 755 patients].\",\"authors\":\"B Wiesner, G Cramer, U Hamel, G Roth\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>755 patients were treated because of tuberculosis from 1984-1989. The treatment was standardized according to the recommendations. INH and RMP were used in over 95% as in the hospital as in the ambulatory phase. During the period of 6 yrs. the use of SM was markedly reduced (21.8%) while the use of PZA increased from 14.6% to 55.0%. At least four drugs were used in 22.5%. In 36.2% mycobacteria were found only before starting treatment. After four weeks treatment further 45.1% were negative. Adverse reactions were registered in 9.3%. Concomitant diseases rendering the treatment were observed in 24.7%. Ten patients died because of tuberculosis. Until now only 3 patients had relapses. Controlled treatment is valuable and therefore recommended.</p>\",\"PeriodicalId\":76840,\"journal\":{\"name\":\"Zeitschrift fur Erkrankungen der Atmungsorgane\",\"volume\":\"177 1-2\",\"pages\":\"71-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur Erkrankungen der Atmungsorgane\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Erkrankungen der Atmungsorgane","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Standardized controlled antitubercular therapy and results in 755 patients].
755 patients were treated because of tuberculosis from 1984-1989. The treatment was standardized according to the recommendations. INH and RMP were used in over 95% as in the hospital as in the ambulatory phase. During the period of 6 yrs. the use of SM was markedly reduced (21.8%) while the use of PZA increased from 14.6% to 55.0%. At least four drugs were used in 22.5%. In 36.2% mycobacteria were found only before starting treatment. After four weeks treatment further 45.1% were negative. Adverse reactions were registered in 9.3%. Concomitant diseases rendering the treatment were observed in 24.7%. Ten patients died because of tuberculosis. Until now only 3 patients had relapses. Controlled treatment is valuable and therefore recommended.