A comparison of intralesional triamcinolone acetonide injection and incision-curettage for chalazion treatment

Objective: To compare the efficacy of intralesional triamcinolone acetonide with surgical incision and curettage in patients with chalazion. Material and Method: This longitudinal interventional study was carried out during 1 st September 2015 to 31 st August 2016 at Kamlesh Netralaya Hospital at Ambikapur, Chhattisgarh in central India. Total 60 patients with Chalazion of ( ≥ 2 mm in size) were randomly divided into two groups of 30 patients each. The first group of patients (N=30) was treated by 0.1 to 0.2 mL intralesional triamcinolone acetonide injection (40 mg/mL) and the second group of patients (N=30) were treated surgically by incision-curettage. Post steroid injection, the reduction in chalazion size was measured at 2 weeks and at 4 weeks. Results: Out of 60 patients, 58.33% were females with mean age of 31.8 ± 9.1 years. There were total 79 chalazion in two groups. Among those treated using intralesional triamcinolone acetonide (ILTA), 29 (70.73%) chalazion resolved at 2 week. The unresolved chalazion were repeated the ILTA injection at 2 nd week and followed till 4 week. The mean 11-point numerical rating scale (NRS) score for pain intensity was significantly lower in ILTA group as compared to IC group (2.3± 0.42 vs 6.7 ± 1.2, P-value = 0.001). Conclusion: The results of intralesional triamcinolone acetonide injection treatment are comparable to that of surgical incision and curettage (IC) after second injection. Patients experienced less pain and were more satisfied with the intralesional triamcinolone acetonide injection. supports the use of for