[槲皮素在实验性冠状动脉闭塞再灌注中的心脏保护作用]。

Farmakologiia i toksikologiia Pub Date : 1991-11-01
Iu N Kolchin, N P Maksiutina, P P Balanda, A I Luĭk, V N Bulakh, A A Moĭbenko
{"title":"[槲皮素在实验性冠状动脉闭塞再灌注中的心脏保护作用]。","authors":"Iu N Kolchin,&nbsp;N P Maksiutina,&nbsp;P P Balanda,&nbsp;A I Luĭk,&nbsp;V N Bulakh,&nbsp;A A Moĭbenko","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In experimental myocardial infarction in dogs caused by 60-minute occlusion of the coronary artery with the subsequent 24-hour reperfusion, the administration of quercetin solution (50 mg/kg) was found to improve the contractile function of the left ventricular myocardium, to decrease the incidence of heart rate and conductivity disorders, to contribute to limitation of the ischemic damage area, to exert the protective effect on the ultrastructure of the coronary arteries that can promote the preservation of the vessels' integrity, the improvement of the coronary circulation and the prevention of intravascular thrombus formation.</p>","PeriodicalId":12237,"journal":{"name":"Farmakologiia i toksikologiia","volume":"54 6","pages":"20-3"},"PeriodicalIF":0.0000,"publicationDate":"1991-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The cardioprotective action of quercetin in experimental occlusion and reperfusion of the coronary artery in dogs].\",\"authors\":\"Iu N Kolchin,&nbsp;N P Maksiutina,&nbsp;P P Balanda,&nbsp;A I Luĭk,&nbsp;V N Bulakh,&nbsp;A A Moĭbenko\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In experimental myocardial infarction in dogs caused by 60-minute occlusion of the coronary artery with the subsequent 24-hour reperfusion, the administration of quercetin solution (50 mg/kg) was found to improve the contractile function of the left ventricular myocardium, to decrease the incidence of heart rate and conductivity disorders, to contribute to limitation of the ischemic damage area, to exert the protective effect on the ultrastructure of the coronary arteries that can promote the preservation of the vessels' integrity, the improvement of the coronary circulation and the prevention of intravascular thrombus formation.</p>\",\"PeriodicalId\":12237,\"journal\":{\"name\":\"Farmakologiia i toksikologiia\",\"volume\":\"54 6\",\"pages\":\"20-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Farmakologiia i toksikologiia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Farmakologiia i toksikologiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

在冠状动脉闭塞60分钟后24小时再灌注的实验性心肌梗死中,槲皮素溶液(50 mg/kg)可改善左心室心肌收缩功能,降低心率和电导障碍的发生率,有助于限制缺血损伤面积。对冠状动脉超微结构发挥保护作用,促进保持血管完整性,改善冠状动脉循环,防止血管内血栓形成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The cardioprotective action of quercetin in experimental occlusion and reperfusion of the coronary artery in dogs].

In experimental myocardial infarction in dogs caused by 60-minute occlusion of the coronary artery with the subsequent 24-hour reperfusion, the administration of quercetin solution (50 mg/kg) was found to improve the contractile function of the left ventricular myocardium, to decrease the incidence of heart rate and conductivity disorders, to contribute to limitation of the ischemic damage area, to exert the protective effect on the ultrastructure of the coronary arteries that can promote the preservation of the vessels' integrity, the improvement of the coronary circulation and the prevention of intravascular thrombus formation.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信