天然口香糖:制备纳米载体的一种选择

S. Rohilla, Gitika Gitika, D. Bhagwat, A. Rohilla
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引用次数: 0

摘要

树胶多糖及其纳米结构最终用于各种食品和非食品工业。它们因其组成、无毒和生物相容性而引起了人们的兴趣。目前正在研究它们作为口服药物化合物的给药系统。天然胶由于其独特的特性,在给药系统领域引起了越来越多的关注。它们来源于细菌、植物和藻类。它们具有良好的生物相容性和生物可降解性,被认为是有吸引力的潜在药物载体。它们在肠道中膨胀,并被结肠微生物群降解。将原始化合物与其他聚合物混合以根据要求改变其性能。树胶和树胶衍生的化合物可以用来制备微纳米制剂,这些制剂可以通过不同的途径给药。在这篇综述中,我们详细概述了最近在制药技术中得到广泛研究的牙龈微粒子和纳米粒子的研究。本文综述了影响微粒子和纳米粒子系统性能的最关键因素及其作为给药系统的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Natural gum: an option to prepare nanocarriers
The tree gum polysaccharide and their nanostructure are used eventually in various food and non-food industries. They attracted interest because of their makeup, non-toxicity and biological compatibility. They are currently being investigated as delivery systems for oral medicinal compounds. Natural gums have attracted more interest in the area of drug delivery systems due to their unique attributes. They are derived from bacteria, plants and algae. They are thought to be attractive prospective medication carriers as they have excellent biocompatibility and biodegradability. They swell in the intestine and are degraded by the colon microbiome. The original compounds are blended with other polymers to modify their properties as per requirements. Gums and gum-derived compounds can be used to prepare micro and nanoformulations that can deliver the drugs via different routes. In this review, We detailed and outlined the most recent studies on micro-and nanoparticles made from gums that have been extensively researched in pharmaceutical technology. This review focuses on the most crucial elements influencing the properties of micro-and nanoparticle systems and their applications as medication delivery systems.
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