[暴露于抗肿瘤制剂的埃利希腹水癌细胞能量代谢系统紊乱的高分辨率31P-NMR研究]。

Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1991-09-01

N A Semenova, E P Shchelok, L A Ostrovskaia, L A Sibel'dina

{"title":"[暴露于抗肿瘤制剂的埃利希腹水癌细胞能量代谢系统紊乱的高分辨率31P-NMR研究]。","authors":"N A Semenova, E P Shchelok, L A Ostrovskaia, L A Sibel'dina","doi":"","DOIUrl":null,"url":null,"abstract":"The disturbance in energetic metabolism of Ehrlich ascite carcinoma cells during antitumor drug treatment was examined using high-resolution 31P-NMR. The value of antitumor drug effect was shown to be characterized by the kinetics of ATP and KF level alteration in tumor cells. The results correlated with the indexes of therapeutical activity of studied drugs.","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":" 5","pages":"794-8"},"PeriodicalIF":0.0000,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[A high-resolution 31P-NMR study of the disorders in the energy metabolic system of Ehrlich ascites cancer cells exposed to antitumor preparations].\",\"authors\":\"N A Semenova, E P Shchelok, L A Ostrovskaia, L A Sibel'dina\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The disturbance in energetic metabolism of Ehrlich ascite carcinoma cells during antitumor drug treatment was examined using high-resolution 31P-NMR. The value of antitumor drug effect was shown to be characterized by the kinetics of ATP and KF level alteration in tumor cells. The results correlated with the indexes of therapeutical activity of studied drugs.\",\"PeriodicalId\":14529,\"journal\":{\"name\":\"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia\",\"volume\":\" 5\",\"pages\":\"794-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

采用高分辨率31P-NMR检测了抗肿瘤药物治疗对埃利希腹水癌细胞能量代谢的干扰。肿瘤细胞内ATP和KF水平变化的动力学表征了抗肿瘤药物作用的价值。结果与所研究药物的治疗活性指标相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[A high-resolution 31P-NMR study of the disorders in the energy metabolic system of Ehrlich ascites cancer cells exposed to antitumor preparations].

The disturbance in energetic metabolism of Ehrlich ascite carcinoma cells during antitumor drug treatment was examined using high-resolution 31P-NMR. The value of antitumor drug effect was shown to be characterized by the kinetics of ATP and KF level alteration in tumor cells. The results correlated with the indexes of therapeutical activity of studied drugs.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Izvestiia Akademii nauk SSSR. Seriia biologicheskaia

自引率

0.00%

发文量