[不同菌株耐药链霉菌夹竹桃霉素形成与耐药性的相互关系]。

Mikrobiologicheskii zhurnal Pub Date : 1991-09-01

A A Shevchenko, A F Tyshchenko, L B Ryzhakova, B P Matseliukh

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引用次数: 0

摘要

研究了不同抗生素形成水平的夹竹桃霉素菌株对其自身抗生素的耐药性。获得的高活性菌株对夹竹桃霉素具有双重抗性，活性提高50%。用HELC法对初始菌株和生产的高活性菌株合成的齐墩霉素磷酸物质进行了鉴定。

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[The interrelation between the formation of oleandomycin and the resistance to it in different strains of Streptomyces antibioticus].

Strains, producers of oleandomycin, with different level of antibiotic-formation have been studied for their resistance to their own antibiotic. The obtained highly active strain possesses double resistance to oleandomycin and 50% higher activity. Identity of oleandomycin phosphate substances synthesized by initial and produced highly active strains is shown by the HELC method.

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Mikrobiologicheskii zhurnal

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