无冷冻切片膀胱部分切除术1例

Kevin Anthony Glorius Tampubolon, S. Pramod
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摘要

背景:膀胱癌是一种常见的泌尿系统癌症,如果治疗不当,发病率和死亡率都很高。目前,部分膀胱切除术作为一种发病率较低且肿瘤有效的治疗方法再次出现。在此,我们对5例膀胱部分切除术无冷冻切片的患者进行了正确的诊断和手术治疗,并回顾了该手术的结果。病例介绍:根据病史、体格检查、ct扫描及组织病理学检查确诊。所有病例均行部分膀胱切除术,包括腹腔镜部分膀胱切除术。通过组织学检查,我们发现4例膀胱腺癌,1例尿路上皮癌伴肉瘤样变异。我们的手术技术是从膀胱镜检查开始的。我们在肿瘤周围1cm处切除肿瘤。肿瘤切除后,我们封闭膀胱,评估膀胱容量,最小容量为200cc。然后用双层技术封闭膀胱,并分别封闭肌肉、筋膜和皮肤。术后6个月和12个月随访观察肿瘤进展或复发情况。本病例无术后并发症。我们所有的病例都没有抱怨,没有进展、复发和转移迹象。结论:冷冻切片在膀胱部分切除术中并不是强制性的,其结果对手术缘无显著影响。膀胱部分切除术效果良好,患者生活质量得到改善,膀胱功能得以保留。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case Series of Partial Cystectomy without Frozen Section
Background: Bladder cancer is a common type of urinary system cancer in the world with high morbidity and mortality if not managed optimally. Currently, partial cystectomy has experienced a resurgence as a less morbid and oncologically effective treatment. Here, we appropriately diagnosed and surgically treated 5 patients with partial cystectomy without frozen section and reviewed the outcome of this procedure. Case presentation: The diagnosis was made based on the history of illness, physical examination, CT-Scan, and confirmed by histopathological examination. A partial cystectomy was performed in all cases, which include laparoscopic partial cystectomy. Based on histological examination, we found that 4 cases in this study were adenocarcinoma bladder and 1 case was urothelial carcinoma cells with sarcomatoid variant. Our surgical technique started with doing a cystoscopy first. We performed excision of the tumor with lateral margin 1cm around the tumor. After resection of the tumor, we closed the bladder and evaluated the capacity of the bladder, which was 200cc minimal capacity. Then we closed the bladder with the double layer technique and closed the muscle, fascia, and skin, respectively. Follow-up was performed 6 and 12 months after surgery to observe progression or recurrence of the tumor. There was no postoperative complication in our case. All of our cases had no complaints and no sign of progression, recurrence, and metastatic sign. Conclusion: A frozen section has not been proven to be mandatory in partial cystectomy and the results had no significant effect in surgical margins. A Partial cystectomy had a good result and improved the quality of patient life with preserved the bladder function.
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