[经口给予肝素-乙酰水杨酸复合物的大鼠血液抗凝系统]。

Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1991-07-01

B A Kudriashov, L A Liapina, V E Pastorova, M V Kondashevskaia

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引用次数: 0

摘要

体外获得肝素/乙酰水杨酸复合物(1:9和10:1)。单次或慢性(7-8天)每次给予大鼠0.1%的肝素/乙酰水杨酸复合物溶液(0.3 ml/200 g体重)，可增强血浆的抗凝血性能，提高稳定纤维蛋白的纤溶活性，降低凝血酶诱导的血小板聚集。

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[The blood anticoagulant system in rats perorally administered a heparin-acetylsalicylic acid complex].

Heparin/acetylsalicylate complexes (1:9 and 10:1) were obtained in vitro. Single or chronic (7-8 days) per os administration to white rats of 0.1% solution of the heparin/acetylsalicylate complex (0.3 ml/200 g body weight) enhanced anticoagulative properties of blood plasma, increased the fibrinolytic activity in respect of stabilized fibrin, and diminished the thrombin-induced platelet aggregation.

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Izvestiia Akademii nauk SSSR. Seriia biologicheskaia

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