Ebstein异常，可能与药物病因有关?病例报告

Heart Research – Open Journal Pub Date : 2021-12-31 DOI:10.17140/hroj-8-158

B. Animasahun, O. A. Ajayi, F. O. Lawani, E. Disu

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引用次数: 0

摘要

Ebstein畸形是一种先天性心脏畸形，其特征是三尖瓣向下移位到右心室。这是罕见的，发病率为20万分之一。病因不明。我们的患者在妊娠四周左右暴露于蒿甲醚-氨苯曲明、环丙沙星和布洛芬(以前与Ebstein异常无关)。妊娠33周时的一次产科扫描是诊断的第一个线索。

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Ebstein’s Anomaly, Possible Newly Implicated Drug Aetiology? A Case Report

Ebstein’s anomaly is a congenital malformation of the heart that is characterized by downward displacement of an abnormal tricuspid valve into the right ventricle. It is rare, with an incidence of 1 in 200,000 live births. Etiology is unknown. Our patient was exposed to artemether-lumefantrine, ciprofloxacin, and ibuprofen (not previously linked with Ebstein’s anomaly) at about four weeks of gestation. An obstetric scan at 33 weeks’ gestation, was the first clue to the diagnosis.

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Heart Research – Open Journal

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