利用单输入自主模糊纳米粒子控制肿瘤生长

F. Razmi, R. Moghaddam, A. Rowhanimanesh
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引用次数: 3

摘要

本文将单输入模糊控制器应用于自主药包纳米粒子(ADENPs),以抑制肿瘤的生长。所提出的腺嘌呤腺苷肽,在局部癌组织中大量释放药物,有效地减少了对正常组织的破坏。考虑肿瘤生长速率和所用药物的反馈值来确定药物的释放量。与纳米机器人相比,纳米粒子的一些显著特点是它们能够从正常组织中识别癌组织和它们简单的结构。纳米粒子已成为纳米科学研究的热点,人们在纳米粒子的制造方面做了许多努力。仿真结果表明,所提出的控制方法不仅有效地减少了癌变组织,而且显著降低了药物的副作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Control of cancer growth using single input autonomous fuzzy Nano-particles
In this paper a single input fuzzy controller is applied on autonomous drug-encapsulated nanoparticles (ADENPs) to restrict the cancer growth. The proposed ADENPs, swarmly release the drug in local cancerous tissue and effectively decreases the destruction of normal tissue. The amount of released drug is defined considering to feed backed values of tumor growth rate and the used drug. Some significant characteristics of Nano particles compared to Nano-robots is their ability to recognize the cancerous tissue from the normal one and their simple structure. Nano particles became an attractive topic in Nano science and many efforts have been done to manufacture these particles. Simulation results show that the proposed controlling method not only decreases the cancerous tissue effectively but also reduces the side effects of drug impressively.
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