男性乳腺癌:当前要点与回顾

Kadam Ss, T. Kadam
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引用次数: 0

摘要

背景:男性乳腺癌是一种非常罕见的疾病,但一些报道的病例系列表明其发病率在过去25年中呈上升趋势。男性乳腺癌的病因学在许多方面与女性不同。文献缺乏支持男性乳腺癌治疗的前瞻性随机证据。只有回顾性证据可用,所有指南都是根据现有的最佳女性乳腺癌治疗数据推断出来的。因此,我们回顾、整理并尝试呈现最好的文献,这些文献强调了男性乳腺癌的治疗。据报道,男性乳腺癌的发病率约占男性所有癌症的1.2%-2%,而在所有男性乳腺癌中,男性和女性乳腺癌的发病率都不到1%。如果它累及两个乳房,那么它就变成了一种非常罕见的情况,只占所有男性乳腺癌的1%。老年男性最常被诊断为乳腺癌,他们大约比女性大5到10岁。男性患乳腺癌最常见的原因是体内雌性激素过多,所有导致雌性激素过多的情况都会增加患癌症的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Male Breast Cancer: Current Essentials & Review
Background: Breast cancer in male is a very rare condition but some of the reported case series had shown that its incidence is increasing over the last 25 years. The etiology of breast cancer in males differs from that of females in many ways. The literature lacks the prospective randomized evidences supporting the treatment of male breast cancer. Only retrospective evidences are available and all guidelines are extrapolated from the best available data of treatment of female breast cancer. Therefore, we have reviewed, compiled and tried to present the best available literature which highlights the treatment of male breast cancer .The reported incidence of breast cancer in men is around 1.2%-2% of all cancers in males and less than 1% of all breast cancers in both sexes. If it involves both breasts then it becomes an extremely uncommon condition which accounts for only 1% of all male breast cancer. Elderly males are most commonly diagnosed with breast cancer and they are approximately 5 to 10 years older than the women. The most common reason of breast cancer in males is excess of estrogen in the body and all conditions which leads to hyperestrogenism are responsible for increasing the risk of cancer.
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