H Schima, C Schlusche, B V Jeremejev, I Schor, G Geihseder, M R Müller, U Losert
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引用次数: 0
摘要
在体外实验中，研究了离心血泵对红细胞弹性的影响。分别用低溶血电位和高溶血电位的无叶式和叶轮式血泵泵送新鲜牛血液(泵送容积1L，流量5l /min vs 150mmhg，泵送时间6小时)。用激光衍射法测定红细胞的弹性。从弹性238 +/- 39开始，6小时内的总体变化为12 +/- 38，而控制值的变化为-13 +/- -58。即使是溶血电位非常高(溶血指数21.9)的泵也没有引起相关的弹性变化。结论是:1)弹性不是评价离心泵的有用参数，2)离心泵引起的机械损伤不会对红细胞的弹性特性产生相关的永久性改变，至少在体外条件下是这样。
Influence of centrifugal blood pumps on the elasticity of erythrocytes.
The influence of centrifugal blood pumps on the elasticity of erythrocytes was tested in an in vitro set-up. Fresh bovine blood was pumped by vaneless and impeller blood pumps with low and high hemolytic potential (1L priming volume, flow 5 L/min versus 150 mmHg, pumping time 6 hours). The elasticity of the red blood cells was measured by laser diffraction. Starting with an elasticity of 238 +/- 39, the overall change during 6 hours was 12 +/- 38 compared to a change of the control value of -13 +/- -58. Even a pump with very high hemolytic potential (Hemolysis index 21.9) did not cause relevant changes of elasticity. It is concluded that 1) elasticity is not a useful parameter to use in the evaluation of centrifugal pumps, and 2) the mechanical trauma caused by centrifugal pumps produces no relevant permanent alteration of the elastic properties of red blood cells, at least under in-vitro conditions.
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