登革热患者的微创手术

S. Yasri, V. Wiwanitkit
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摘要

登革热是一种重要的虫媒病毒感染,目前已成为若干国家的公共卫生威胁。流行区扩大到非热带地区导致若干国家出现新发感染。登革热通常是一种伴有出血性并发症的急性发热性疾病(1)。登革热的出血性并发症具有广泛的临床范围,有时是严重的(2)。手术治疗的要求有时是外科医生关注的一个重要问题。一些严重出血的登革热患者,如消化道大出血,可能需要手术治疗,微创手术在这些病例中起着重要作用。在这种情况下,内窥镜治疗被证明是有用的(3,4)。然而,在这些情况下,通常需要输血来纠正止血问题,因为仅内窥镜注射治疗通常不足以治疗(5)。在登革热患者中使用微创手术的建议仍然存在争议。一些研究报道,由于登革热患者的微创手术效果有限,因此不建议对其进行微创手术(6)。根据马来西亚最近的一份报告,Ng等人得出结论,“穿孔胃溃疡的早期手术干预对于防止进一步并发症和降低死亡风险至关重要(7)。”腹腔镜方法也被报道为一种安全的诊断方法(8)。在选择登革热患者的微创手术时,需要考虑几个因素,尤其是患者的病情。在高危情况下,应考虑重组止血药物的支持一级预防(9)。在需要紧急手术的情况下,建议使用经典方法,适当的血小板输注计划有助于改善临床结果(10)。在这个问题上的具体研究是有趣的,值得推荐。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Minimally Invasive Surgery in Dengue Patient
Dear Editor, Dengue is an important arbovirus infection that becomes the public health threaten in several countries, at present. The expansion of the endemic area to non-tropical area results in new emerging infection in several countries. The dengue is generally an acute febrile illness with hemorrhagic complication (1). The hemorrhagic complication in dengue has a wide clinical spectrum and it is sometime serious (2). The requirement of surgical management is sometimes an important concern for the surgeon. Some dengue patients with severe bleeding such as massive gastrointestinal bleeding might need surgical management and the minimally invasive surgery plays an important role in those cases. The endoscopic management is proved useful in that situation (3, 4). Nevertheless, the transfusion is usually required for correction of the hemostatic problem in those cases since only endoscopic injection treatment is usually not adequate for management (5). The recommendation on using minimally invasive surgery in dengue patient is still controversial. Some studies report that, the minimally invasive surgery in dengue patient is discouraged due to the limitation of effectiveness (6). According to a recent report from Malaysia, Ng et al. concluded that “early surgical intervention in perforated gastric ulcer is vital in preventing further complication and reducing the risk of mortality (7).” In case with suspicious hemoperitoneum due to dengue, the laparoscope approach is also reported as a safe diagnostic approach (8). In order to select a minimally invasive surgery in dengue patient, several considerations, especially patient’s condition are important. A supportive primary prevention by recombinant hemostatic agent should be considered in case with high risk (9). In case which require emergency surgery, the use of classical approach is indicated and the appropriated plan for platelet transfusion helps improve clinical outcome (10). A specific study in this issue is interesting and recommended.
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