[含有胆固醇或非那嗪自由基的低聚脱氧核糖核苷酸的烷基化衍生物在与laidlawii PG-8相互作用时的稳定性]。

Mikrobiologicheskii zhurnal Pub Date : 1991-07-01

L P Panchenko, O V Egorov, I G Skripal', A S Raĭt, E M Ivanova, V F Zarytova, V V Vlasov

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引用次数: 0

摘要

研究了胆固醇和非那嗪残基在3′端保护的癸甲酰酯烷基化衍生物与laidlawi细胞PG-8相互作用过程中的稳定性。结果表明，所研究的试剂在支原体生物聚合物烷基化所需的时间内不会被支原体的核酸酶裂解。

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[The stability of the alkylating derivatives of oligodeoxyribonucleotides containing a cholesterol or phenazine radical added to the 3'-termination during their interaction with Acholeplasma laidlawii PG-8].

Stability of alkylating derivatives of decathymidylates protected on the 3'-terminal by cholesterol and phenazine residues has been studied in the process of their interaction with cells of Acholeplasma laidlawii PG-8. It is shown that the studied reagents are not split by nucleases of A. laidlawii PG-8 for the time necessary for alkylation of mycoplasma biopolymers.

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Mikrobiologicheskii zhurnal

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