{"title":"心脏再生研究进展","authors":"Flora Chen","doi":"10.1145/3444884.3444897","DOIUrl":null,"url":null,"abstract":"Heart disease is one of the diseases with high mortality. When heart disease occurs, a large number of cardiomyocytes die and the heart function is severely damaged. In severe cases, it may lead to death. The research on heart regeneration has become a key issue in the treatment of heart diseases. This review article discusses the factors that influence heart regeneration. Promoters include ERBB2, NRG1, estrogen, and miRNA 19-72 clusters whereas inhibitors consist of innervation, thyroid T4 and miRNA-128. The recognition of factors that influence cardiomyocyte proliferation and heart regeneration may provide reveal new therapeutic possibilities in the treatment of cardiovascular diseases.","PeriodicalId":142206,"journal":{"name":"Proceedings of the 2020 7th International Conference on Biomedical and Bioinformatics Engineering","volume":"34 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Review for Heart Regeneration\",\"authors\":\"Flora Chen\",\"doi\":\"10.1145/3444884.3444897\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Heart disease is one of the diseases with high mortality. When heart disease occurs, a large number of cardiomyocytes die and the heart function is severely damaged. In severe cases, it may lead to death. The research on heart regeneration has become a key issue in the treatment of heart diseases. This review article discusses the factors that influence heart regeneration. Promoters include ERBB2, NRG1, estrogen, and miRNA 19-72 clusters whereas inhibitors consist of innervation, thyroid T4 and miRNA-128. The recognition of factors that influence cardiomyocyte proliferation and heart regeneration may provide reveal new therapeutic possibilities in the treatment of cardiovascular diseases.\",\"PeriodicalId\":142206,\"journal\":{\"name\":\"Proceedings of the 2020 7th International Conference on Biomedical and Bioinformatics Engineering\",\"volume\":\"34 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-11-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 2020 7th International Conference on Biomedical and Bioinformatics Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1145/3444884.3444897\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 2020 7th International Conference on Biomedical and Bioinformatics Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1145/3444884.3444897","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Heart disease is one of the diseases with high mortality. When heart disease occurs, a large number of cardiomyocytes die and the heart function is severely damaged. In severe cases, it may lead to death. The research on heart regeneration has become a key issue in the treatment of heart diseases. This review article discusses the factors that influence heart regeneration. Promoters include ERBB2, NRG1, estrogen, and miRNA 19-72 clusters whereas inhibitors consist of innervation, thyroid T4 and miRNA-128. The recognition of factors that influence cardiomyocyte proliferation and heart regeneration may provide reveal new therapeutic possibilities in the treatment of cardiovascular diseases.
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