主观记忆障碍患者与轻度认知障碍患者的神经认知功能

Mi-Ae Kang, Yongmae Baek
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引用次数: 15

摘要

背景:本研究探讨主观记忆障碍患者与轻度认知障碍患者神经认知功能的特征差异。方法:将主诉记忆障碍患者分为主观记忆障碍患者(SMI, n=42)和轻度认知障碍患者(MCI, n=42),根据患者的韩语版最小状态检查、日常生活活动能力(ADL)、临床痴呆评分及神经科医师的诊断和评价。使用首尔神经心理筛查组和老年抑郁量表比较重度精神障碍组和轻度精神障碍组的神经认知功能和抑郁评分。结果:重度精神障碍组在言语学习延迟测试中注意力集中、视觉空间构建能力正常,在记忆巩固加工中出现抑郁和缺陷。MCI组在注意力方面也没有缺陷,但在言语学习、视觉记忆测试和额叶/执行功能的延迟回忆和识别测试中表现出损伤。结论:轻度认知损伤组在言语学习延迟回忆和识别测试中表现出更明显的神经认知缺陷;视觉记忆的编码、存储和检索;和命名能力相比讨论了本研究的意义和建议,并提出了进一步研究的建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Neurocognitive Function Between the Patients Who had Subjective Memory Impairment and Mild Cognitive Impairment
Background: This study investigated the characteristic differences of neurocognitive function in patients with subjective memory impairment and in those with mild cognitive impairment. Methods: Patients with complaints of subjective memory impairment were categorized into subjective memory impairment (SMI, n=42) and mild cognitive impairment (MCI, n=42) based on their scores in the Korean version of MiniMental State Examination, Activities of Daily Living (ADL), and Clinical Dementia Rating and the neurologist’s diagnosis and evaluation. The neurocognitive function and depression rating between the SMI and the MCI groups were compared using the Seoul Neuropsychological Screening Battery and the Geriatric Depression Scale. Results: The SMI group showed normal concentration, visual-spatial construction ability, and depression and deficits in the processing of memory consolidation through the delay test of verbal learning. The MCI group also showed no deficits in concentration but showed impairments in delayed recall and recognition test of verbal learning, visual memory test, and frontal lobe/executive functions. Conclusion: The MCI group showed more distinctive neurocognitive deficits in delayed recall and recognition test of verbal learning; encoding, storage, and retrieval of visual memory; and naming ability compared to the SMI group. The implications and suggestions of this study and further research were discussed.
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