小儿神经血管疾病

H. Mccullagh, T. Patankar, T. Goddard, A. Tyagi
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引用次数: 0

摘要

儿童神经血管疾病的频谱包括几个条件,如动静脉畸形(AVM),动脉瘤和海绵状血管瘤,发生在成人。尽管在病理上有相似之处,但与成人相比,儿童血管疾病在表现、部位和治疗方面存在差异。有些疾病是儿科人群所特有的,如盖伦静脉畸形或早产儿的脑室内出血,以及其他主要发生在儿童身上的疾病,尽管在成人中也见过,如莫亚病。血管内治疗、放射外科和血管病变多模式管理的最新进展增加了治疗儿童这些病变的选择。识别海绵状瘤和烟雾病的潜在基因异常有望揭示这些疾病的发病机制。在儿科人群中常见的神经血管疾病将在本章中讨论,重点是那些主要发生在儿童身上的疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Paediatric neurovascular disorders
The spectrum of paediatric neurovascular disorders includes several conditions like arteriovenous malformation (AVM), aneurysm, and cavernous malformations that occur in adults. Despite the similarity in pathology there are differences in presentation, location, and management of vascular disorders in children as compared to adults. There are disorders that are peculiar to the paediatric population like vein of Galen malformations or intraventricular haemorrhage in premature infants and others that occur predominantly in children though are seen in adults such as moya disorder. Recent advances in endovascular therapy, radiosurgery, and multimodality management of vascular lesions have increased the options available to manage these lesions in children. Identification of underlying gene abnormalities in cavernomas and moya moya disease promises to shed new light on the pathogenesis of these disorders. The common neurovascular disorders seen in the paediatric population are discussed in this chapter with the focus on those seen predominantly in children.
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