{"title":"新型IrOx/SiO2/W交叉点存储器用于赖氨酸氧化酶样2 (LOXL2)乳腺癌生物标志物检测","authors":"S. Jana, S. Samanta, S. Roy, J. Qiu, S. Maikap","doi":"10.1109/VLSI-TSA.2018.8403860","DOIUrl":null,"url":null,"abstract":"Novel IrO<inf>x</inf>/SiO<inf>2</inf>/W 10x10 µm<sup>2</sup> cross-point structure has been introduced for high-density resistive memory as well as urea/LOXL2 sensing for the first time. The Ir<sup>0</sup>/Ir<sup>3+</sup>/Ir<sup>4+</sup> oxidation states are confirmed by X-ray photo-electron spectroscopy (XPS) analysis. A dc endurance of > 1000 cycles at low current compliance (CC) of 200 nA and long program/erase (P/E) endurance of >10<sup>10</sup> cycles with a small pulse width of 100 ns are obtained. Super-nernstian pH sensitivity of 140 mV/pH with 99.45% linearity, and LOXL2 with a low concentration of 1 pM through porous IrO<inf>x</inf> membrane are obtained.","PeriodicalId":209993,"journal":{"name":"2018 International Symposium on VLSI Technology, Systems and Application (VLSI-TSA)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Novel IrOx/SiO2/W cross-point memory for lysyl-oxidase-like-2 (LOXL2) breast cancer biomarker detection\",\"authors\":\"S. Jana, S. Samanta, S. Roy, J. Qiu, S. Maikap\",\"doi\":\"10.1109/VLSI-TSA.2018.8403860\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Novel IrO<inf>x</inf>/SiO<inf>2</inf>/W 10x10 µm<sup>2</sup> cross-point structure has been introduced for high-density resistive memory as well as urea/LOXL2 sensing for the first time. The Ir<sup>0</sup>/Ir<sup>3+</sup>/Ir<sup>4+</sup> oxidation states are confirmed by X-ray photo-electron spectroscopy (XPS) analysis. A dc endurance of > 1000 cycles at low current compliance (CC) of 200 nA and long program/erase (P/E) endurance of >10<sup>10</sup> cycles with a small pulse width of 100 ns are obtained. Super-nernstian pH sensitivity of 140 mV/pH with 99.45% linearity, and LOXL2 with a low concentration of 1 pM through porous IrO<inf>x</inf> membrane are obtained.\",\"PeriodicalId\":209993,\"journal\":{\"name\":\"2018 International Symposium on VLSI Technology, Systems and Application (VLSI-TSA)\",\"volume\":\"46 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2018 International Symposium on VLSI Technology, Systems and Application (VLSI-TSA)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/VLSI-TSA.2018.8403860\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 International Symposium on VLSI Technology, Systems and Application (VLSI-TSA)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/VLSI-TSA.2018.8403860","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Novel IrOx/SiO2/W cross-point memory for lysyl-oxidase-like-2 (LOXL2) breast cancer biomarker detection
Novel IrOx/SiO2/W 10x10 µm2 cross-point structure has been introduced for high-density resistive memory as well as urea/LOXL2 sensing for the first time. The Ir0/Ir3+/Ir4+ oxidation states are confirmed by X-ray photo-electron spectroscopy (XPS) analysis. A dc endurance of > 1000 cycles at low current compliance (CC) of 200 nA and long program/erase (P/E) endurance of >1010 cycles with a small pulse width of 100 ns are obtained. Super-nernstian pH sensitivity of 140 mV/pH with 99.45% linearity, and LOXL2 with a low concentration of 1 pM through porous IrOx membrane are obtained.