{"title":"非辐照复发性青少年咽乳头状瘤病的恶性转化","authors":"A. Hakeem, Jagadish Tubachi, Raja Kumar, S. Pawar","doi":"10.5005/JP-JOURNALS-10003-1047","DOIUrl":null,"url":null,"abstract":"Very few cases of spontaneous malignant transformation of nonirradiated recurrent juvenile laryngeal papillomatosis (JLP) have beenreported in literature. We document a case of invasive laryngeal carcinoma arising in pre-existing juvenile laryngeal papillomatosis. Aftermultiple CO2 Laser resections, a 29-year-old female, non-smoker, who had never received radiation therapy, developed a florid exophytictransglottic squamous cell carcinoma. Therefore, regular extensive biopsies and careful histopathological examination are required in casesof JLP. We also emphasize the need to maintain a high index of suspicion for malignant transformation in long standing cases.","PeriodicalId":235775,"journal":{"name":"Otorhinolaryngology Clinics An International Journal","volume":"2 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Malignant Transformation of Nonirradiated Recurrent JuvenileLaryngeal Papillomatosis\",\"authors\":\"A. Hakeem, Jagadish Tubachi, Raja Kumar, S. Pawar\",\"doi\":\"10.5005/JP-JOURNALS-10003-1047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Very few cases of spontaneous malignant transformation of nonirradiated recurrent juvenile laryngeal papillomatosis (JLP) have beenreported in literature. We document a case of invasive laryngeal carcinoma arising in pre-existing juvenile laryngeal papillomatosis. Aftermultiple CO2 Laser resections, a 29-year-old female, non-smoker, who had never received radiation therapy, developed a florid exophytictransglottic squamous cell carcinoma. Therefore, regular extensive biopsies and careful histopathological examination are required in casesof JLP. We also emphasize the need to maintain a high index of suspicion for malignant transformation in long standing cases.\",\"PeriodicalId\":235775,\"journal\":{\"name\":\"Otorhinolaryngology Clinics An International Journal\",\"volume\":\"2 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Otorhinolaryngology Clinics An International Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5005/JP-JOURNALS-10003-1047\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Otorhinolaryngology Clinics An International Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5005/JP-JOURNALS-10003-1047","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Malignant Transformation of Nonirradiated Recurrent JuvenileLaryngeal Papillomatosis
Very few cases of spontaneous malignant transformation of nonirradiated recurrent juvenile laryngeal papillomatosis (JLP) have beenreported in literature. We document a case of invasive laryngeal carcinoma arising in pre-existing juvenile laryngeal papillomatosis. Aftermultiple CO2 Laser resections, a 29-year-old female, non-smoker, who had never received radiation therapy, developed a florid exophytictransglottic squamous cell carcinoma. Therefore, regular extensive biopsies and careful histopathological examination are required in casesof JLP. We also emphasize the need to maintain a high index of suspicion for malignant transformation in long standing cases.
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