[不可切除的4期食管癌对联合放化疗反应良好- 1例报告]。

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-07-20
E Hirao, T Saito, A Kuwahara, Y Shigemitsu, T Kinoshita, K Shimoda, M Miyahara, M Kobayashi
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引用次数: 0

摘要

我们报告了一例不能切除的4期食管癌患者,经顺铂(C)、长春地西(V)、派霉素(P)联合放疗(R)后,长期存活。患者男性,53岁,入院时诊断为癌,长度8 cm,位于食管IuCe区,右侧锁骨下淋巴结转移。原发及转移病灶放疗总剂量60gy,同时行2周期CVP化疗。原发病灶内镜下肿物变为平坦带小糜烂,治疗结束后右侧锁骨下转移淋巴结消失,CT未见。本病例的客观反应被确定为部分反应,因为在平坦的病变处仍发现癌细胞。出院后,连续3年给予9个周期的CVP治疗。目前,患者活得很好,尽管部分原发性食管病变经活检证实为恶性肿瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Unresectable stage 4-cancer of the esophagus well responded to combined chemoradiotherapy--a case report].

We experienced a long-term survived case with unresectable Stage 4 esophageal carcinoma well responded to chemoradiotherapy of combination of cisplatin (C), vindesine (V) and peplomycin (P) with radiotherapy (R). The patient was a male, aged 53, and diagnosed to have carcinoma, 8 cm in length, located at the IuCe region of the esophagus and right subclavicular lymph node metastasis on admission. He received radiotherapy at total dose of 60 Gy for the primary and metastatic lesions, and also 2 cycle CVP chemotherapy concomitantly. The mass of the primary lesion endoscopically changed to a flat area with small erosion while the right subclavicular metastatic node disappeared and was not found on CT after the end of the treatment. Objective response of this case was determined to the partial response since carcinoma cells were still found at the flat lesion. After discharge, 9 cycles of CVP therapy were further given in 3-year periods. At present, the patient is alive well although a part of the primary esophageal lesion is proved to have malignancy on biopsy.

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