西替利嗪和依巴斯汀对皮肤对组胺反应的药理学调节。

Dermatologica Pub Date : 1991-01-01 DOI:10.1159/000247671

J Rivest, K Despontin, L Ghys, J P Rihoux, J M Lachapelle

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引用次数: 26

摘要

比较单次口服西替利嗪10mg和依巴斯汀10mg在皮肤水平的外周h1抑制作用。在双盲随机交叉条件下对9名健康受试者进行研究。两种药物在24 h内均显著有效，西替利嗪的抑制作用明显更迅速、更显著。

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Pharmacological modulation by cetirizine and ebastine of the cutaneous reactivity to histamine.

The peripheral H1-inhibiting effects of cetirizine 10 mg and ebastine 10 mg were compared at the skin level after single oral administration. The study was performed in 9 healthy subjects under double-blind randomized crossover conditions. Both drugs were significantly effective up to 24 h. The suppressive effect of cetirizine was significantly more rapid and more marked.

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Dermatologica

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