伴发病毒性病原体对卡氏肺囊虫肺炎病程的影响。

The Journal of protozoology Pub Date : 1991-11-01
S A Bozzette, J Arcia, A E Bartok, L M McGlynn, J A McCutchan, D D Richman, R Spragg, S A Spector
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引用次数: 0

摘要

我们进行了一项大型回顾性研究,以评估从艾滋病卡氏肺囊虫肺炎患者的呼吸道分泌物中培养巨细胞病毒的影响。327例卡氏肺囊虫患者中有220例(67%)发现卡氏肺囊虫,106例(48%)发现巨细胞病毒。巨细胞病毒阳性和阴性患者在基线时相似,住院天数相似,但早期氧合恶化的发生率较低,重症监护天数较少,插管次数较少,30天生存率较高。本研究中观察到的巨细胞病毒阳性患者较好的短期预后可能与巨细胞病毒的免疫抑制作用有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of concomitant viral pathogens on the course of Pneumocystis carinii pneumonia.

A large retrospective study was conducted to evaluate the impact of culturing cytomegalovirus from the respiratory secretions of AIDS patients with Pneumocystis carinii pneumonia. Pneumocystis carinii was found in 220 (67%) of 327 episodes and cytomegalovirus was found in 106 (48%) of the P. carinii-positive patients. Cytomegalovirus-positive and -negative patients were similar at baseline and had a similar number of hospital days, but had a lower incidence of early deterioration in oxygenation, fewer intensive-care days, were less frequently intubated, and had a higher 30-day survival. The better short-term outcome of cytomegalovirus positive patients observed in this study may relate to the immunosuppressive effects of cytomegalovirus.

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