Effects Of Methanolic Extract Of Aspilia Africana Leaf On The Ovarian Tissues And Weights Of Wistar Rats

25 Cyclic female wistar rats were randomized into 5 groups (A, B, C, D & E) of 5 animals each. They were administered 0.00mg/Kg B.W, 100mg/KgB.W, 150 mg/Kg B.W, 200 mg/Kg B.W, 250 mg/Kg B.W & 300 mg/Kg B.W. of methanolic extract of Aspilia africana respectively, once in a day, everyday of the week for 30 days. The animals' weights were taking before, midway and at the end of the experiment. Reduced wet weights of the ovaries were recorded at the end of experiment. Routine histological analysis of the Ovaries revealed derangement of granulosa cells, degeneration and reduction of follicles and poor vascularity of ovarian stroma.