Karius-ity and the Cat: Diagnosing Hepatosplenic Bartonella Using Next Generation DNA Sequencing and Imaging

Case Summary: A 23-year-old female with common variable immunodeficiency (CVID), presented with intermittent epigastric pain, which would eventually spread to her entire abdomen. She had night sweats, chills, and regular stools. She had been evaluated twice over the last two months for posterior cervical lymphadenopathy and similar abdominal symptoms, which were attributed to a possible EBV infection. Her exam was notable for diffuse abdominal tenderness, worse in the epigastric region, without rebound or guarding. Additionally, she had a non-tender fixed lymph node in the right posterior cervical chain. Her medical …