人类健康和过敏反应的营养药品

Anamika Basu, Anasua Sarkar, Piyali Basak
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引用次数: 2

摘要

过敏是免疫系统对一种叫做抗原的物质的过度反应,比如草的花粉、尘螨等。对抗疗法中用于治疗过敏的药物有不良的副作用。由于对抗性药物的副作用,药用植物的使用变得流行。营养保健品是在维持人体正常生理功能方面起重要作用的食品。肥大细胞是一种重要的免疫细胞,几乎存在于我们身体的所有部位,在它们的颗粒囊中含有组胺、白三烯,以及嗜碱性细胞,它们是过敏症状的原因。根据来源,肥大细胞稳定剂可分为三类,即合成、半合成和天然。从自然资源中获得的肥大细胞稳定剂可以从不同种类的化合物中获得,如类黄酮、香豆素、酚类、萜类、生物碱等。在这本书的章节中,使用计算生物学技术,例如分子对接等,突出了它们中存在的活性成分及其作用方式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nutraceuticals for Human Health and Hypersensitivity Reaction
An allergy is an overreaction of the immune system to a substance called an antigen, e.g., pollen from grasses, dust mites, etc. The drugs used for allergy in allopathy have undesirable side effects. The use of medicinal plants becomes popular due to the adverse effects of allopathic drugs. Nutraceuticals are food playing a significant role in maintaining normal physiological function. Mast cells are immunologically important cells found in almost all parts of our body, and contain histamines, leukotrienes within their granular sacs, along with those of basophils, are responsible for the symptoms of allergy. According to sources mast cell stabilizers can be classified into three categories, e.g., synthetic, semi synthetic and natural. Mast cell stabilising agents from natural resources can be obtained from different group of compounds, e.g., flavonoids, coumarins, phenols, terpenoids, alkaloids. In this book chapter, the active constituents present in them and their mode of action are highlighted using techniques of computational biology, e.g., molecular docking, etc.
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