Samyogita Choudhary, Sayan Chakraborty, L. Goswami, Dhiman Sen
{"title":"一起草甘膦中毒案例","authors":"Samyogita Choudhary, Sayan Chakraborty, L. Goswami, Dhiman Sen","doi":"10.18231/j.ijfmts.2023.017","DOIUrl":null,"url":null,"abstract":"Glyphosate is a commercially available herbicide which also acts as a human toxin. It produces a wide range of clinical manifestations ranging from throat irritation, GI tract erosion and bleeding, surfactant elated liver and kidney injury, metabolic acidosis and even death. We are reporting a case of a 36 year old female who consumed around 400ml of the pesticide and presented to our tertiary care hospitals after 12 hours of ingestion, in a state of renal shutdown, Severe acidosis and hyperkalemia and shock. We started on hemoperfusion and CRRT apart from the initial resuscitation. She was successfully treated and discharged home. This case report emphasise on the use of hemoperfusion toxin removing cartridge for sever glyphosate poisoning as there is no known antidote of this toxin and also the mechanism of toxicity is still not well-established?","PeriodicalId":163055,"journal":{"name":"IP International Journal of Forensic Medicine and Toxicological Sciences","volume":"12 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A case of glyphosate poisoning\",\"authors\":\"Samyogita Choudhary, Sayan Chakraborty, L. Goswami, Dhiman Sen\",\"doi\":\"10.18231/j.ijfmts.2023.017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Glyphosate is a commercially available herbicide which also acts as a human toxin. It produces a wide range of clinical manifestations ranging from throat irritation, GI tract erosion and bleeding, surfactant elated liver and kidney injury, metabolic acidosis and even death. We are reporting a case of a 36 year old female who consumed around 400ml of the pesticide and presented to our tertiary care hospitals after 12 hours of ingestion, in a state of renal shutdown, Severe acidosis and hyperkalemia and shock. We started on hemoperfusion and CRRT apart from the initial resuscitation. She was successfully treated and discharged home. This case report emphasise on the use of hemoperfusion toxin removing cartridge for sever glyphosate poisoning as there is no known antidote of this toxin and also the mechanism of toxicity is still not well-established?\",\"PeriodicalId\":163055,\"journal\":{\"name\":\"IP International Journal of Forensic Medicine and Toxicological Sciences\",\"volume\":\"12 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IP International Journal of Forensic Medicine and Toxicological Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijfmts.2023.017\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IP International Journal of Forensic Medicine and Toxicological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijfmts.2023.017","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Glyphosate is a commercially available herbicide which also acts as a human toxin. It produces a wide range of clinical manifestations ranging from throat irritation, GI tract erosion and bleeding, surfactant elated liver and kidney injury, metabolic acidosis and even death. We are reporting a case of a 36 year old female who consumed around 400ml of the pesticide and presented to our tertiary care hospitals after 12 hours of ingestion, in a state of renal shutdown, Severe acidosis and hyperkalemia and shock. We started on hemoperfusion and CRRT apart from the initial resuscitation. She was successfully treated and discharged home. This case report emphasise on the use of hemoperfusion toxin removing cartridge for sever glyphosate poisoning as there is no known antidote of this toxin and also the mechanism of toxicity is still not well-established?