[乙醇对猫外侧前庭核神经元背景活动的影响]

Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01
V S Raĭtses, D V Semeniv
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引用次数: 0

摘要

单次静脉注射乙醇(1 g/kg)对实验猫影响95%所研究的外侧前庭核神经元。在大多数(56.5%)具有不间断心律失常型主要高频背景活动的神经元中,乙醇给药导致冲动频率降低84-93%;14.5%的爆发组活动神经元在给药20 ~ 30 min后,通过对背景活动的急剧抑制直至完全停止,表现出平均放电频率、爆发时间延长和脉冲数量的显著增加。23.6%的神经元在整个观察过程中由于乙醇效应出现了明显的兴奋效应,其中以背景活动的低频为主。通常,恢复到初级水平的活动甚至在90分钟后也没有出现。相同剂量的乙醇反复使用会产生累积效应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Influence of ethanol on the background activity of neurons in the lateral vestibular nucleus of the cat].

Single intravenous administration of ethanol (1 g/kg) to experimental cats influences 95% of investigated neurons of the lateral vestibular nucleus. In most (56.5%) neurons possessing primarily high-frequency background activity of the uninterrupted arrhythmic type ethanol administration has caused a decrease in the impulsation frequency by 84-93%; 14.5% neurons of the burst-group activity demonstrate a primary distinct increase of the average frequency of discharges, prolongation of bursts and the numbers of impulses in them changed 20-30 min after ethanol administration by sharp inhibition of the background activity up to its complete ceasing. A distinct exciting effect has arisen due to the ethanol effect during the whole period of observation in 23.6% of neurons mostly with primary low frequency of the background activity. The rehabilitation of the activity up to the primary level as a rule did not appear even 90 min later. Repeated administration of ethanol in the same dose has induced a cumulative effect.

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