广泛性腮腺炎治疗期间口服液中骨吸收标志物的动态变化

A. Y. Lukash, O. Fastovets, S. Pavlov
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引用次数: 0

摘要

分子生物学标记在牙周病患者中的应用是牙科临床中一个很有前途的课程。首先,这是由于疾病的患病率和危险因素呈上升趋势,这使得相关的发现对早期发现和预防治疗有效的方法。本研究选取30例ⅰ、ⅱ严重程度的广泛性牙周炎患者。在实验组患者中,采用免疫分析法测定治疗动态中口腔液中骨髓代谢标志物(MMP-8)的水平。在研究过程中,这种酶的含量被发现表明牙龈炎症过程转化为牙槽骨的破坏。20。余。Lukash等人。口腔液中MMP-8的浓度及其动态变化表明,该标记物可指示牙周组织炎症破坏过程的过程,因此有可能用于诊断和监测广泛性牙周炎的治疗结果
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dynamics of markers of bone resorption in oral fluid in patients with generalized parodontitis during its treatment
One of the promising courses in the clinical dentistry is the use of molecular biological markers in patients with periodontal disease. First of all, this is due to the rising trend in the prevalence and risk factors of the disease, which makes relevant finding effective methods for early detection and preventive treatment. 30 patients diagnosed with generalized periodontitis of the I and II degree of severity were selected for the research. In the experimental groups of patients, an immunoassay was used to determine the marker level of bone marrow metabolism (MMP-8) in the oral fluid, in the dynamics of treatment. During the study, the content of this enzyme was found to be indicative of the transformation of the inflammatory process in the gums into the destruction of the alveolar bone. 20 A. Yu. Lukash et al. The obtained values of the concentration of MMP-8 in the oral fluid, as well as their dynamics, proved this marker to be indicative of the course of the inflammatory-destructive process in periodontal tissues, and therefore the possibility of its application for the diagnosis and monitoring of the results of treatment of generalized periodontitis
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