一种识别糖尿病视网膜病变生物标志物的新方法

P. Rayavel, C. Murukesh
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引用次数: 1

摘要

随着抗血管内皮生长因子(VEGF)药物如雷尼单抗和贝伐单抗的出现,视网膜外液和视网膜下液的存在已成为需要抗VEGF治疗的主要信号,并用于识别疾病活动性和辅助糖尿病视网膜病变的治疗。尽管糖尿病视网膜病变(DR)的治疗取得了进展,但早期发现对于DR的治疗至关重要,并且仍然是一个重大障碍。临床DR可与非增殖性DR区分开来,后者没有明显的视力丧失和视力威胁后果,如黄斑水肿和糖尿病视网膜病变引起的增殖性视网膜病变。提出的方法强化了在彩色眼底图像中准确检测糖尿病视网膜病变发展风险较高的生物标志物的过程。此外,所提出的方法可以用来量化这些病变及其分布有效,如在实验结果中所示。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Novel Approach for Identification of Biomakers in Diabetic Retinopathy Recognition
In the emergence of anti-Antivascular endothelial growth factor (VEGF) drugs such as ranibizumab and bevacizumab, it has become obvious that the presence of outer retinal and subretinal fluid is the primary signal of the need for anti-VEGF therapy, and used to identify disease activity and assist diabetic retinopathy treatment. Despite advancements in diabetic retinopathy (DR) treatments, early detection is critical for DR management and remains a significant barrier. Clinical DR can be distinguished from non proliferative DR without visible vision loss and vision-threatening consequences such as macular edoema and proliferative retinopathy by retinal alterations in diabetes. The proposed method aggrandize the process of accurate detection of biomakers responsible for higher risk of diabetic retinopathy development in color fundus images. Furthermore, the proposed approach could be employed to quantify these lesions and their distributions efficientively as evident in the experimentation results.
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