包装红细胞(PRC)血液成分在加工和储存过程中的测定

Francisca Romana Sri Supadmi, D. Artini, Nurpuji Mumpuni
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摘要

-需要对PRC组件进行质量测试,以确保一致的加工和存储过程,以获得最佳的修复效果。血液储存过程中的溶血是红细胞储存最严重的表现,是评价PRC[1]、[2]质量的重要参数。本研究旨在测量PRC溶血水平,作为加工和储存过程中的质量指标。这是一项使用比较分析方法(学生t检验)的观察性描述性研究。之前对建筑物内采集的血液进行PRC研究发现,溶血率在第0天平均升高,随着下一次处理逐渐升高,即使在储存结束时仍低于0.8%的标准。在第14天,移动单位(MU)的PRC溶血率显著升高。溶血率在第7天的PRC提取时从0.3增加到0.5。此外,两组的PRC溶血率在贮藏期结束前持续增加,特别是在第35天,但仍低于0.8%的水平。t检验结果显示显著水平为(p) 0.001,即低于0.05。因此,可以得出结论,输血单位血液采样和流动单位(MU)血液采集活动在PRC溶血方面存在显着评分差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Measurement of Pack Red Cells (PRC) Blood Components During Processing and Storage
— The quality test of the PRC components is needed to ensure a consistent processing and storage processes for an optimal healing effect. Hemolysis during blood storage is the most severe manifestation of erythrocyte storage and is an important parameter for assessing the quality of PRC [1], [2]. This study aims to measure the level of PRC hemolysis as an indicator of quality during processing and storage. This is an observational descriptive study using a comparative analytical approach (student t-test). The previous researches on PRC on the bloods collected inside the building revealed that the average increase in hemolysis occurred on the 0th day along with the gradual increase in the next processing even though it was still under the standard of below 0.8% at the end of storage. It was also noted that PRC hemolysis on mobile unit (MU) collection significantly increased on 14th day. The most significant increase in hemolysis occurred at PRC drawing of MU on 7th day from 0.3 to 0.5. Furthermore, the PRC hemolysis of the two groups continued to increase variably until the end of the storage period, particularly on day 35 although it remained below the level of 0.8%. The t-test results show a significant level of (p) 0.001, that is lower than 0.05. Thus, it can be concluded that there is a significant score difference in the PRC hemolysis between the Blood Transfusion Unit blood sampling and mobile unit (MU) blood collection activities.
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