AAA和Acuros XB对宫颈癌高密度金属植入物的临床剂量学影响

M. Bhushan, G. Yadav, D. Tripathi, L. Kumar, V. Kishore, R. Chowdhary, G. Kumar, Soumya Datta, S. Mitra, M. Gairola
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引用次数: 2

摘要

背景:金属植入物在放射治疗中对肿瘤靶区和关键器官的定位存在困难。四野盒技术是治疗盆腔恶性肿瘤的常规方法。研究目的:研究目的是评估计算算法在金属植入治疗宫颈癌中的剂量学影响。材料与方法:采用石蜡包覆铁棒评价金属种植体对梁特性的影响。测量并分析组织幻像比(TPR20,10)等光束特性。对15例宫颈金属假体植入与不植入的患者进行了比较。计划处方剂量为45 Gy/25组分。使用AAA算法计算平面图,并对相同的监视器单元使用acros XB (AXB)和铅笔束卷积算法重新计算。采用RTOG和Quantec协议进行计划评价。结果:透射率和TPR20、10随视场大小和光束能量的增加而增加。表面剂量也随场的大小而增加。AAA与AXB的计划靶体积的d98%和d2 %有显著差异。在V15Gyof小肠的情况下,通过三种算法计算4F方案,4FN (AAA)明显优于4F方案。分析数据表明,高z材料引起了显著的衰减。整合指数分析结果表明,所有案例的整合指数均为bbb1。结论:在制定宫颈癌金属假体治疗方案时,AAA算法将是更合适的选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical dosimetric impact of AAA and Acuros XB on high-density metallic implants in case of carcinoma cervix
Background: Metallic implant in radiotherapy leads to difficulty in tumor target and critical organ delineation. Four-field box technique is conventional approach to treat pelvic malignancies. Aim of the Study: The aim of study is to evaluate the dosimetric impact of calculation algorithms in the treatment of carcinoma cervix with metallic implants. Materials and Methods: A paraffin wax-coated iron rod was used to evaluate the beam characteristics under the influence of metallic implant. Beam characteristics such as tissue phantom ratio (TPR20,10) were measured and analyzed. 15 patients with and without metallic prosthesis of carcinoma cervix were compared in the study. Planning was done for the prescription dose of 45 Gy/25 fractions. Plans were calculated using AAA algorithm and recalculated using Acuros XB (AXB) and pencil beam convolution algorithms for the same monitor units. RTOG and Quantec Protocol were used for plan evaluation. Results: Transmission and TPR20,10increases with field size and beam energy. Surface dose Dsalso increases with field size. D98%and D2%of planning target volume showed a significant difference for AAA versus AXB. 4FN (AAA) are significantly better for all the 4F plans, calculated by three algorithms in case of V15Gyof small bowel. Analyzed data indicated the significant attenuation caused by high-Z material. Analyzed value of conformity index showed that value of index comes >1 in all the cases. Conclusion: The results indicate that when creating treatment plans for cervical cancer lesions with metallic prosthesis, the AAA algorithm would be a more appropriate choice.
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