{"title":"细胞信号转导的信息热力学","authors":"T. Tsuruyama","doi":"10.5772/INTECHOPEN.79951","DOIUrl":null,"url":null,"abstract":"Intracellular signal transduction is the most important research topic in cell biology, and for many years, model research by system biology based on network theory has long been in progress. This article reviews cell signaling from the viewpoint of information thermo- dynamics and describes a method for quantitatively describing signaling. In particular, a theoretical basis for evaluating the efficiency of intracellular signal transduction is presented in which information transmission in intracellular signal transduction is maxi-mized by using entropy coding and the fluctuation theorem. An important conclusion is obtained: the average entropy production rate is constant through the signal cascade.","PeriodicalId":205001,"journal":{"name":"Cell Signalling - Thermodynamics and Molecular Control","volume":"35 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Information Thermodynamics of Cell Signal Transduction\",\"authors\":\"T. Tsuruyama\",\"doi\":\"10.5772/INTECHOPEN.79951\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Intracellular signal transduction is the most important research topic in cell biology, and for many years, model research by system biology based on network theory has long been in progress. This article reviews cell signaling from the viewpoint of information thermo- dynamics and describes a method for quantitatively describing signaling. In particular, a theoretical basis for evaluating the efficiency of intracellular signal transduction is presented in which information transmission in intracellular signal transduction is maxi-mized by using entropy coding and the fluctuation theorem. An important conclusion is obtained: the average entropy production rate is constant through the signal cascade.\",\"PeriodicalId\":205001,\"journal\":{\"name\":\"Cell Signalling - Thermodynamics and Molecular Control\",\"volume\":\"35 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-11-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell Signalling - Thermodynamics and Molecular Control\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5772/INTECHOPEN.79951\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell Signalling - Thermodynamics and Molecular Control","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5772/INTECHOPEN.79951","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Information Thermodynamics of Cell Signal Transduction
Intracellular signal transduction is the most important research topic in cell biology, and for many years, model research by system biology based on network theory has long been in progress. This article reviews cell signaling from the viewpoint of information thermo- dynamics and describes a method for quantitatively describing signaling. In particular, a theoretical basis for evaluating the efficiency of intracellular signal transduction is presented in which information transmission in intracellular signal transduction is maxi-mized by using entropy coding and the fluctuation theorem. An important conclusion is obtained: the average entropy production rate is constant through the signal cascade.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
