控制大流行性流感的最佳抗病毒治疗策略

Qingxin Zhang
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引用次数: 0

摘要

本文讨论了流感爆发的最佳抗病毒治疗策略。最优控制问题是指以最小的干预成本使感染人数最小化。证明了控制问题的最优解的存在性。此外,利用庞特里亚金极大值原理,得到时变抗病毒治疗的最优策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimal antiviral treatment strategies for the control of pandemic influenza
This paper discusses an optimal antiviral treatment strategy for the outbreak of influenza. The optimal control problem is formulated by minimizing the number of infected individuals at a minimal intervention cost. The existence of an optimal solution for the control problem is proved. In addition, with the Pontryagin's Maximum Principle, the time-varying optimal strategy of antiviral treatment is obtained.
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